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Suppression of miR-708 inhibits the Wnt/β-catenin signaling pathway by activating DKK3 in adult B-all

Inactivation of Dickkopf-3 (DKK3) is closely associated with a poor prognosis in various solid tumor and hematologic malignancies. Promoter hypermethylation is one potential cause of DKK3 inactivation. However, whether other mechanisms lead to DKK3 inactivation and the subsequent effects of these in...

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Detalles Bibliográficos
Autores principales: Zhang, Yingjie, Li, Huibo, Cao, Rongyi, Sun, Lili, Wang, Yan, Fan, Shengjin, Zhao, Yanqiu, Kong, Desheng, Cui, Lin, Lin, Leilei, Wang, Ke, Li, Yinghua, Zhou, Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5609988/
https://www.ncbi.nlm.nih.gov/pubmed/28969056
http://dx.doi.org/10.18632/oncotarget.19342