γH2AX, 53BP1 and Rad51 protein foci changes in mesenchymal stem cells during prolonged X-ray irradiation

At high exposure levels ionizing radiation is a carcinogen. Little is known about how human stem cells, which are known to contribute to tumorigenesis, respond to prolonged radiation exposures. We studied formation of DNA double strand breaks, accessed as γH2AX and 53BP1 foci, in human mesenchymal s...

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Detalles Bibliográficos
Autores principales: Tsvetkova, Anastasia, Ozerov, Ivan V., Pustovalova, Margarita, Grekhova, Anna, Eremin, Petr, Vorobyeva, Natalia, Eremin, Ilya, Pulin, Andrey, Zorin, Vadim, Kopnin, Pavel, Leonov, Sergey, Zhavoronkov, Alex, Klokov, Dmitry, Osipov, Andreyan N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610005/
https://www.ncbi.nlm.nih.gov/pubmed/28969073
http://dx.doi.org/10.18632/oncotarget.19203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610005/
https://www.ncbi.nlm.nih.gov/pubmed/28969073
http://dx.doi.org/10.18632/oncotarget.19203

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