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Cardioprotective effects of 5‐hydroxymethylfurfural mediated by inhibition of L‐type Ca(2+) currents

BACKGROUND AND PURPOSE: The antioxidant 5‐hydroxymethylfurfural (5‐HMF) exerts documented beneficial effects in several experimental pathologies and is currently tested as an antisickling drug in clinical trials. In the present study, we examined the cardiovascular effects of 5‐HMF and elucidated th...

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Detalles Bibliográficos
Autores principales: Wölkart, G, Schrammel, A, Koyani, C N, Scherübel, S, Zorn‐Pauly, K, Malle, E, Pelzmann, B, Andrä, M, Ortner, A, Mayer, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610158/
https://www.ncbi.nlm.nih.gov/pubmed/28768052
http://dx.doi.org/10.1111/bph.13967