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The number of key carcinogenic events can be predicted from cancer incidence
The widely accepted multiple-hit hypothesis of carcinogenesis states that cancers arise after several successive events. However, no consensus has been reached on the quantity and nature of these events, although “driver” mutations or epimutations are considered the most probable candidates. By usin...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group UK
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610194/ https://www.ncbi.nlm.nih.gov/pubmed/28939880 http://dx.doi.org/10.1038/s41598-017-12448-7 |