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Cell culture: complications due to mechanical release of ATP and activation of purinoceptors

There is abundant evidence that ATP (adenosine 5′-triphosphate) is released from a variety of cultured cells in response to mechanical stimulation. The release mechanism involved appears to be a combination of vesicular exocytosis and connexin and pannexin hemichannels. Purinergic receptors on cultu...

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Detalles Bibliográficos
Autores principales: Burnstock, Geoffrey, Knight, Gillian E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610203/
https://www.ncbi.nlm.nih.gov/pubmed/28434079
http://dx.doi.org/10.1007/s00441-017-2618-8