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Dual “mAb” HER family blockade in head and neck cancer human cell lines combined with photon therapy

Head and neck cancer stem cells (CSCs) are highly resistant to treatment. When EGFR is overexpressed in head and neck squamous cell carcinoma (HNSCC), HER2 and HER3 are also expressed. The aim of the present study was to investigate the effect of HER1/2/3 blockade through a combination of cetuximab...

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Detalles Bibliográficos
Autores principales: Guy, Jean-Baptiste, Méry, Benoîte, Ollier, Edouard, Espenel, Sophie, Vallard, Alexis, Wozny, Anne-Sophie, Simonet, Stéphanie, Lauret, Alexandra, Battiston-Montagne, Priscillia, Ardail, Dominique, Alphonse, Gersende, Rancoule, Chloé, Rodriguez-Lafrasse, Claire, Magné, Nicolas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610257/
https://www.ncbi.nlm.nih.gov/pubmed/28939847
http://dx.doi.org/10.1038/s41598-017-12367-7