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Characterization of the antifungal functions of a WGA-Fc (IgG2a) fusion protein binding to cell wall chitin oligomers

The majority of therapeutic strategies for mycosis require the protracted administration of antifungals, which can result in significant toxicities and have unacceptable failure rates. Hence, there is an urgent need for the development of improved therapeutic approaches, and monoclonal antibody-base...

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Detalles Bibliográficos
Autores principales: Liedke, Susie Coutinho, Miranda, Daniel Zamith, Gomes, Kamilla Xavier, Gonçalves, Jorge Luis S., Frases, Susana, Nosanchuk, Joshua D., Rodrigues, Marcio L., Nimrichter, Leonardo, Peralta, José Mauro, Guimarães, Allan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610272/
https://www.ncbi.nlm.nih.gov/pubmed/28939893
http://dx.doi.org/10.1038/s41598-017-12540-y