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Apicomplexan actin polymerization depends on nucleation

Filamentous actin is critical for apicomplexan motility and host cell invasion. Yet, parasite actin filaments are short and unstable. Their kinetic characterization has been hampered by the lack of robust quantitative methods. Using a modified labeling method, we carried out thorough biochemical cha...

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Detalles Bibliográficos
Autores principales: Kumpula, Esa-Pekka, Pires, Isa, Lasiwa, Devaki, Piirainen, Henni, Bergmann, Ulrich, Vahokoski, Juha, Kursula, Inari
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610305/
https://www.ncbi.nlm.nih.gov/pubmed/28939886
http://dx.doi.org/10.1038/s41598-017-11330-w