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In vivo target exploration of apidaecin based on Acquired Resistance induced by Gene Overexpression (ARGO assay)

Identifying the target molecules of antimicrobial agents is essential for assessing their mode of action. Here, we propose Acquired Resistance induced by Gene Overexpression (ARGO) as a novel in vivo approach for exploring target proteins of antimicrobial agents. The principle of the method is based...

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Detalles Bibliográficos
Autores principales: Matsumoto, Ken’ichiro, Yamazaki, Kurato, Kawakami, Shun, Miyoshi, Daichi, Ooi, Toshihiko, Hashimoto, Shigeki, Taguchi, Seiichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610309/
https://www.ncbi.nlm.nih.gov/pubmed/28939819
http://dx.doi.org/10.1038/s41598-017-12039-6