Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane

Signal transduction by receptor tyrosine kinases (RTKs) involves complex ligand- and time-dependent changes in conformation and modification state. High resolution structures are available for individual receptors dimers, but less is known about receptor clusters that form in plasma membranes compos...

Descripción completa

Detalles Bibliográficos
Autores principales: Werbin, Jeffrey L., Avendaño, Maier S., Becker, Verena, Jungmann, Ralf, Yin, Peng, Danuser, Gaudenz, Sorger, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610318/
https://www.ncbi.nlm.nih.gov/pubmed/28939861
http://dx.doi.org/10.1038/s41598-017-12257-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610318/
https://www.ncbi.nlm.nih.gov/pubmed/28939861
http://dx.doi.org/10.1038/s41598-017-12257-y

Ejemplares similares