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Multiplexed Exchange-PAINT imaging reveals ligand-dependent EGFR and Met interactions in the plasma membrane
Signal transduction by receptor tyrosine kinases (RTKs) involves complex ligand- and time-dependent changes in conformation and modification state. High resolution structures are available for individual receptors dimers, but less is known about receptor clusters that form in plasma membranes compos...
Autores principales: | Werbin, Jeffrey L., Avendaño, Maier S., Becker, Verena, Jungmann, Ralf, Yin, Peng, Danuser, Gaudenz, Sorger, Peter K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610318/ https://www.ncbi.nlm.nih.gov/pubmed/28939861 http://dx.doi.org/10.1038/s41598-017-12257-y |
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