A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy

Epilepsy may arise following acute brain insults, but no treatments exist that prevent epilepsy in patients at risk. Here we examined whether a combination of two glutamate receptor antagonists, NBQX and ifenprodil, acting at different receptor subtypes, exerts antiepileptogenic effects in the intra...

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Detalles Bibliográficos
Autores principales: Schidlitzki, Alina, Twele, Friederike, Klee, Rebecca, Waltl, Inken, Römermann, Kerstin, Bröer, Sonja, Meller, Sebastian, Gerhauser, Ingo, Rankovic, Vladan, Li, Dandan, Brandt, Claudia, Bankstahl, Marion, Töllner, Kathrin, Löscher, Wolfgang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610327/
https://www.ncbi.nlm.nih.gov/pubmed/28939854
http://dx.doi.org/10.1038/s41598-017-12368-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610327/
https://www.ncbi.nlm.nih.gov/pubmed/28939854
http://dx.doi.org/10.1038/s41598-017-12368-6

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