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A combination of NMDA and AMPA receptor antagonists retards granule cell dispersion and epileptogenesis in a model of acquired epilepsy
Epilepsy may arise following acute brain insults, but no treatments exist that prevent epilepsy in patients at risk. Here we examined whether a combination of two glutamate receptor antagonists, NBQX and ifenprodil, acting at different receptor subtypes, exerts antiepileptogenic effects in the intra...
Autores principales: | Schidlitzki, Alina, Twele, Friederike, Klee, Rebecca, Waltl, Inken, Römermann, Kerstin, Bröer, Sonja, Meller, Sebastian, Gerhauser, Ingo, Rankovic, Vladan, Li, Dandan, Brandt, Claudia, Bankstahl, Marion, Töllner, Kathrin, Löscher, Wolfgang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610327/ https://www.ncbi.nlm.nih.gov/pubmed/28939854 http://dx.doi.org/10.1038/s41598-017-12368-6 |
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