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Fluoxetine and thioridazine inhibit efflux and attenuate crystalline biofilm formation by Proteus mirabilis

Proteus mirabilis forms extensive crystalline biofilms on indwelling urethral catheters that block urine flow and lead to serious clinical complications. The Bcr/CflA efflux system has previously been identified as important for development of P. mirabilis crystalline biofilms, highlighting the pote...

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Detalles Bibliográficos
Autores principales: Nzakizwanayo, Jonathan, Scavone, Paola, Jamshidi, Shirin, Hawthorne, Joseph A., Pelling, Harriet, Dedi, Cinzia, Salvage, Jonathan P., Hind, Charlotte K., Guppy, Fergus M., Barnes, Lara M., Patel, Bhavik A., Rahman, Khondaker M., Sutton, Mark J., Jones, Brian V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610337/
https://www.ncbi.nlm.nih.gov/pubmed/28939900
http://dx.doi.org/10.1038/s41598-017-12445-w