A Single Sphingomyelin Species Promotes Exosomal Release of Endoglin into the Maternal Circulation in Preeclampsia

Preeclampsia (PE), an hypertensive disorder of pregnancy, exhibits increased circulating levels of a short form of the auxillary TGF-beta (TGFB) receptor endoglin (sENG). Until now, its release and functionality in PE remains poorly understood. Here we show that ENG selectively interacts with sphing...

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Detalles Bibliográficos
Autores principales: Ermini, Leonardo, Ausman, Jonathan, Melland-Smith, Megan, Yeganeh, Behzad, Rolfo, Alessandro, Litvack, Michael L., Todros, Tullia, Letarte, Michelle, Post, Martin, Caniggia, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610344/
https://www.ncbi.nlm.nih.gov/pubmed/28939895
http://dx.doi.org/10.1038/s41598-017-12491-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610344/
https://www.ncbi.nlm.nih.gov/pubmed/28939895
http://dx.doi.org/10.1038/s41598-017-12491-4

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