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Combined high dose radiation and pazopanib in metastatic renal cell carcinoma: a phase I dose escalation trial

BACKGROUND: The primary objective was to determine maximum tolerated radiation dose in patients with metastatic renal cell carcinoma on pazopanib treatment. METHODS: Treatment-naïve patients received pazopanib according to standard of care. Stereotactic body radiotherapy (SBRT) was delivered concurr...

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Detalles Bibliográficos
Autores principales: De Wolf, Katrien, Rottey, Sylvie, Vermaelen, Karim, Decaestecker, Karel, Sundahl, Nora, De Lobel, Lizzy, Goetghebeur, Els, De Meerleer, Gert, Lumen, Nicolaas, Fonteyne, Valérie, De Maeseneer, Daan, Ost, Piet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610443/
https://www.ncbi.nlm.nih.gov/pubmed/28938918
http://dx.doi.org/10.1186/s13014-017-0893-x