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miR-19b-3p promotes colon cancer proliferation and oxaliplatin-based chemoresistance by targeting SMAD4: validation by bioinformatics and experimental analyses

BACKGROUND: As a disease with extremely complex molecular mechanisms, many deregulated miRNAs have been identified in colon cancer. Few studies have been performed by using Ingenuity Pathways Analysis (IPA) to predict miRNAs specifically expressed in colon cancer. METHODS: A characteristic microRNA-...

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Detalles Bibliográficos
Autores principales: Jiang, Tao, Ye, Ling, Han, Zhongbo, Liu, Yuan, Yang, Yinxue, Peng, Zhihai, Fan, Junwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610468/
https://www.ncbi.nlm.nih.gov/pubmed/28938919
http://dx.doi.org/10.1186/s13046-017-0602-5