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miR-19b-3p promotes colon cancer proliferation and oxaliplatin-based chemoresistance by targeting SMAD4: validation by bioinformatics and experimental analyses
BACKGROUND: As a disease with extremely complex molecular mechanisms, many deregulated miRNAs have been identified in colon cancer. Few studies have been performed by using Ingenuity Pathways Analysis (IPA) to predict miRNAs specifically expressed in colon cancer. METHODS: A characteristic microRNA-...
Autores principales: | Jiang, Tao, Ye, Ling, Han, Zhongbo, Liu, Yuan, Yang, Yinxue, Peng, Zhihai, Fan, Junwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610468/ https://www.ncbi.nlm.nih.gov/pubmed/28938919 http://dx.doi.org/10.1186/s13046-017-0602-5 |
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