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Effect of Rifampin on the Single-Dose Pharmacokinetics of Oral Cabotegravir in Healthy Subjects

Drug-drug interactions between antiretroviral medications and rifampin complicate the treatment of HIV and tuberculosis coinfection. This study evaluated the effect of rifampin on the pharmacokinetics of oral cabotegravir, an integrase strand transfer inhibitor being investigated for long-acting tre...

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Detalles Bibliográficos
Autores principales: Ford, S. L., Sutton, K., Lou, Y., Zhang, Z., Tenorio, A., Trezza, C., Patel, P., Spreen, W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610536/
https://www.ncbi.nlm.nih.gov/pubmed/28739783
http://dx.doi.org/10.1128/AAC.00487-17