Induction of Mkp-1 and Nuclear Translocation of Nrf2 by Limonoids from Khaya grandifoliola C.DC Protect L-02 Hepatocytes against Acetaminophen-Induced Hepatotoxicity

Drug-induced liver injury (DILI) is a major clinical problem where natural compounds hold promise for its abrogation. Khaya grandifoliola (Meliaceae) is used in Cameroonian traditional medicine for the treatment of liver related diseases and has been studied for its hepatoprotective properties. Till...

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Detalles Bibliográficos
Autores principales: Kouam, Arnaud F., Yuan, Fei, Njayou, Frédéric N., He, Hongtao, Tsayem, Roméo F., Oladejo, Babayemi O., Song, Fuhang, Moundipa, Paul F., Gao, George F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610691/
https://www.ncbi.nlm.nih.gov/pubmed/28974930
http://dx.doi.org/10.3389/fphar.2017.00653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610691/
https://www.ncbi.nlm.nih.gov/pubmed/28974930
http://dx.doi.org/10.3389/fphar.2017.00653

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