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Synthesis and Leishmanicidal Activity of 1-[5-(5-Nitrofuran-2-yl)-1, 3, 4-Thiadiazole-2-yl]-4-BenzoylePiperazines

A series of (5-nitrofuran-2-yl)-1, 3, 4-thiadiazole-2-yl derivatives 6a–6e have been synthesized and screened for in-vitro anti-leishmanial activity against the promastigote form of L. major. The structure of Schiff bases were confirmed by (1)H NMR, IR. Screening results indicate that all of the des...

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Detalles Bibliográficos
Autores principales: Foroumadi, Alireza, Adibi, Hadi, Kabudanian Ardestani, Sussan, Shirooie, Samira, Bozorgomid, Arezoo, Jafari, Ali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610746/
https://www.ncbi.nlm.nih.gov/pubmed/29201081