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Pharmacophore Based Virtual Screening Approach to Identify Selective PDE4B Inhibitors

Phosphodiesterase 4 (PDE4) has been established as a promising target in asthma and chronic obstructive pulmonary disease. PDE4B subtype selective inhibitors are known to reduce the dose limiting adverse effect associated with non-selective PDE4B inhibitors. This makes the development of PDE4B subty...

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Detalles Bibliográficos
Autores principales: Gaurav, Anand, Gautam, Vertika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610747/
https://www.ncbi.nlm.nih.gov/pubmed/29201082