Estrogens Protect Calsequestrin-1 Knockout Mice from Lethal Hyperthermic Episodes by Reducing Oxidative Stress in Muscle

Oxidative stress has been proposed to play a key role in malignant hyperthermia (MH), a syndrome caused by excessive Ca(2+) release in skeletal muscle. Incidence of mortality in male calsequestrin-1 knockout (CASQ1-null) mice during exposure to halothane and heat (a syndrome closely resembling human...

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Detalles Bibliográficos
Autores principales: Michelucci, Antonio, Boncompagni, Simona, Canato, Marta, Reggiani, Carlo, Protasi, Feliciano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610815/
https://www.ncbi.nlm.nih.gov/pubmed/29062464
http://dx.doi.org/10.1155/2017/6936897

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610815/
https://www.ncbi.nlm.nih.gov/pubmed/29062464
http://dx.doi.org/10.1155/2017/6936897

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