Extrinsic Apoptosis Pathway Altered by Glycogen Synthase Kinase-3β Inhibitor Influences the Net Drug Effect on NSC-34 Motor Neuron-Like Cell Survival

Glycogen synthase kinase-3β (GSK-3β) inhibitors have been suggested as a core regulator of apoptosis and have been investigated as therapeutic agents for neurodegenerative diseases, including amyotrophic lateral sclerosis. However, GSK-3β has an interesting paradoxical effect of being proapoptotic d...

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Detalles Bibliográficos
Autores principales: Kim, Jee-Eun, Lim, Jung Hyun, Jeon, Gye Sun, Shin, Je-Young, Ahn, Suk-Won, Kim, Seung Hyun, Lee, Kwang-Woo, Hong, Yoon-Ho, Sung, Jung-Joon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610847/
https://www.ncbi.nlm.nih.gov/pubmed/29082245
http://dx.doi.org/10.1155/2017/4163839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610847/
https://www.ncbi.nlm.nih.gov/pubmed/29082245
http://dx.doi.org/10.1155/2017/4163839

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