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Inhibitors of Protein Methyltransferases and Demethylases

[Image: see text] Post-translational modifications of histones by protein methyltransferases (PMTs) and histone demethylases (KDMs) play an important role in the regulation of gene expression and transcription and are implicated in cancer and many other diseases. Many of these enzymes also target va...

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Detalles Bibliográficos
Autores principales: Kaniskan, H. Ümit, Martini, Michael L., Jin, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610952/
https://www.ncbi.nlm.nih.gov/pubmed/28338320
http://dx.doi.org/10.1021/acs.chemrev.6b00801