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Hippocampal and Cortical Pyramidal Neurons Swell in Parallel with Astrocytes during Acute Hypoosmolar Stress

Normal nervous system function is critically dependent on the balance of water and ions in the extracellular space (ECS). Pathological reduction in brain interstitial osmolarity results in osmotically-driven flux of water into cells, causing cellular edema which reduces the ECS and increases neurona...

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Detalles Bibliográficos
Autores principales: Murphy, Thomas R., Davila, David, Cuvelier, Nicholas, Young, Leslie R., Lauderdale, Kelli, Binder, Devin K., Fiacco, Todd A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611379/
https://www.ncbi.nlm.nih.gov/pubmed/28979186
http://dx.doi.org/10.3389/fncel.2017.00275