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Hippocampal and Cortical Pyramidal Neurons Swell in Parallel with Astrocytes during Acute Hypoosmolar Stress
Normal nervous system function is critically dependent on the balance of water and ions in the extracellular space (ECS). Pathological reduction in brain interstitial osmolarity results in osmotically-driven flux of water into cells, causing cellular edema which reduces the ECS and increases neurona...
Autores principales: | Murphy, Thomas R., Davila, David, Cuvelier, Nicholas, Young, Leslie R., Lauderdale, Kelli, Binder, Devin K., Fiacco, Todd A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611379/ https://www.ncbi.nlm.nih.gov/pubmed/28979186 http://dx.doi.org/10.3389/fncel.2017.00275 |
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