Cargando…

Nrdp1 Increases Ischemia Induced Primary Rat Cerebral Cortical Neurons and Pheochromocytoma Cells Apoptosis Via Downregulation of HIF-1α Protein

Neuregulin receptor degradation protein-1 (Nrdp1) is an E3 ubiquitin ligase that targets proteins for degradation and regulates cell growth, apoptosis and oxidative stress in various cell types. We have previously shown that Nrdp1 is implicated in ischemic cardiomyocyte death. In this study, we inve...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yuan, Yang, Ke, Wang, Ting, Li, Weiping, Jin, Xinchun, Liu, Wenlan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611384/
https://www.ncbi.nlm.nih.gov/pubmed/28979191
http://dx.doi.org/10.3389/fncel.2017.00293