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Nrdp1 Increases Ischemia Induced Primary Rat Cerebral Cortical Neurons and Pheochromocytoma Cells Apoptosis Via Downregulation of HIF-1α Protein
Neuregulin receptor degradation protein-1 (Nrdp1) is an E3 ubiquitin ligase that targets proteins for degradation and regulates cell growth, apoptosis and oxidative stress in various cell types. We have previously shown that Nrdp1 is implicated in ischemic cardiomyocyte death. In this study, we inve...
Autores principales: | Zhang, Yuan, Yang, Ke, Wang, Ting, Li, Weiping, Jin, Xinchun, Liu, Wenlan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611384/ https://www.ncbi.nlm.nih.gov/pubmed/28979191 http://dx.doi.org/10.3389/fncel.2017.00293 |
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