Tumour exosomes from cells harbouring PTPRZ1–MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma

Exosomes are carriers of pro-tumorigenic factors that participate in glioblastoma (GBM) progression, and many fusion genes are strong driver mutations in neoplasia and are involved in tumorigenesis. However, the ability of fusion genes to be transduced by exosomes is unknown. We characterized exosom...

Descripción completa

Detalles Bibliográficos
Autores principales: Zeng, A-L, Yan, W, Liu, Y-W, Wang, Z, Hu, Q, Nie, E, Zhou, X, Li, R, Wang, X-F, Jiang, T, You, Y-P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611480/
https://www.ncbi.nlm.nih.gov/pubmed/28504721
http://dx.doi.org/10.1038/onc.2017.134

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611480/
https://www.ncbi.nlm.nih.gov/pubmed/28504721
http://dx.doi.org/10.1038/onc.2017.134

Ejemplares similares