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Evaluation of Recombinant Multi-Epitope Outer Membrane Protein-Based Klebsiella pneumoniae Subunit Vaccine in Mouse Model

Safety and protective efficacy of recombinant multi-epitope subunit vaccine (r-AK36) was evaluated in a mouse model. Recombinant AK36 protein comprised of immunodominant antigens from outer membrane proteins (Omp’s) of Klebsiella pneumoniae namely OmpA and OmpK36. r-AK36 was highly immunogenic and t...

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Detalles Bibliográficos
Autores principales: Babu, Litty, Uppalapati, Siva R., Sripathy, Murali H., Reddy, Prakash N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611512/
https://www.ncbi.nlm.nih.gov/pubmed/28979250
http://dx.doi.org/10.3389/fmicb.2017.01805