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Structure-Based Prototype Peptides Targeting the Pseudomonas aeruginosa Type VI Secretion System Effector as a Novel Antibacterial Strategy

The type VI secretion system (T6SS) secretes numerous toxins for bacteria-bacteria competition. TplE is a newly identified trans-kingdom toxin secreted by the T6SS in Pseudomonas aeruginosa, while TplEi neutralizes the toxic effect of TplE to protect bacteria autointoxication. Blocking the interacti...

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Detalles Bibliográficos
Autores principales: Gao, Xiaopan, Mu, Zhixia, Qin, Bo, Sun, Yicheng, Cui, Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611513/
https://www.ncbi.nlm.nih.gov/pubmed/28979890
http://dx.doi.org/10.3389/fcimb.2017.00411