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Necroptotic debris including damaged mitochondria elicits sepsis-like syndrome during late-phase tularemia

Infection with Francisella tularensis ssp. tularensis (Ft) strain SchuS4 causes an often lethal disease known as tularemia in rodents, non-human primates, and humans. Ft subverts host cell death programs to facilitate their exponential replication within macrophages and other cell types during early...

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Detalles Bibliográficos
Autores principales: Singh, Anju, Periasamy, Sivakumar, Malik, Meenakshi, Bakshi, Chandra Shekhar, Stephen, Laurie, Ault, Jeffrey G, Mannella, Carmen A, Sellati, Timothy J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611684/
https://www.ncbi.nlm.nih.gov/pubmed/28955505
http://dx.doi.org/10.1038/cddiscovery.2017.56