NCS-Rapgef2, the Protein Product of the Neuronal Rapgef2 Gene, Is a Specific Activator of D1 Dopamine Receptor-Dependent ERK Phosphorylation in Mouse Brain

The neuritogenic cAMP sensor (NCS), encoded by the Rapgef2 gene, links cAMP elevation to activation of extracellular signal-regulated kinase (ERK) in neurons and neuroendocrine cells. Transducing human embryonic kidney (HEK)293 cells, which do not express Rapgef2 protein or respond to cAMP with ERK...

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Detalles Bibliográficos
Autores principales: Jiang, Sunny Zhihong, Xu, Wenqin, Emery, Andrew C., Gerfen, Charles R., Eiden, Maribeth V., Eiden, Lee E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2017
Materias:
New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611689/
https://www.ncbi.nlm.nih.gov/pubmed/28948210
http://dx.doi.org/10.1523/ENEURO.0248-17.2017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611689/
https://www.ncbi.nlm.nih.gov/pubmed/28948210
http://dx.doi.org/10.1523/ENEURO.0248-17.2017

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