Influence of genetic variants on renal uric acid handling in response to frusemide: an acute intervention study

OBJECTIVES: Genetic variation in the renal urate transporters SLC2A9 (GLUT9) and SLC22A11 (OAT4) has been reported to interact with diuretics to increase the risk of developing gout. The aim of this study was to determine whether variation in SLC2A9 or SLC22A11 influences acute renal handling of uri...

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Detalles Bibliográficos
Autores principales: Dalbeth, Nicola, Allan, Jordyn, Gamble, Gregory D, Phipps-Green, Amanda, Flynn, Tanya J, Mihov, Borislav, Horne, Anne, Doughty, Robert, Stamp, Lisa K, Merriman, Tony R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2017
Materias:
Crystal Arthropathies
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611711/
https://www.ncbi.nlm.nih.gov/pubmed/28951782
http://dx.doi.org/10.1136/rmdopen-2016-000424

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611711/
https://www.ncbi.nlm.nih.gov/pubmed/28951782
http://dx.doi.org/10.1136/rmdopen-2016-000424

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