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Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766)

Major depressive disorder (MDD) is a heritable and highly debilitating condition. It is commonly associated with subcortical volumetric abnormalities, the most replicated of these being reduced hippocampal volume. Using the most recent published data from Enhancing Neuroimaging Genetics through Meta...

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Detalles Bibliográficos
Autores principales: Wigmore, E M, Clarke, T-K, Howard, D M, Adams, M J, Hall, L S, Zeng, Y, Gibson, J, Davies, G, Fernandez-Pujals, A M, Thomson, P A, Hayward, C, Smith, B H, Hocking, L J, Padmanabhan, S, Deary, I J, Porteous, D J, Nicodemus, K K, McIntosh, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611720/
https://www.ncbi.nlm.nih.gov/pubmed/28809859
http://dx.doi.org/10.1038/tp.2017.148