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Do regional brain volumes and major depressive disorder share genetic architecture? A study of Generation Scotland (n=19 762), UK Biobank (n=24 048) and the English Longitudinal Study of Ageing (n=5766)
Major depressive disorder (MDD) is a heritable and highly debilitating condition. It is commonly associated with subcortical volumetric abnormalities, the most replicated of these being reduced hippocampal volume. Using the most recent published data from Enhancing Neuroimaging Genetics through Meta...
Autores principales: | Wigmore, E M, Clarke, T-K, Howard, D M, Adams, M J, Hall, L S, Zeng, Y, Gibson, J, Davies, G, Fernandez-Pujals, A M, Thomson, P A, Hayward, C, Smith, B H, Hocking, L J, Padmanabhan, S, Deary, I J, Porteous, D J, Nicodemus, K K, McIntosh, A M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611720/ https://www.ncbi.nlm.nih.gov/pubmed/28809859 http://dx.doi.org/10.1038/tp.2017.148 |
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