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A novel preventive therapy for paclitaxel-induced cognitive deficits: preclinical evidence from C57BL/6 mice
Chemotherapy-induced central nervous system (CNS) neurotoxicity presents an unmet medical need. Patients often report a cognitive decline in temporal correlation to chemotherapy, particularly for hippocampus-dependent verbal and visuo-spatial abilities. We treated adult C57Bl/6 mice with 12 × 20 mg ...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611721/ https://www.ncbi.nlm.nih.gov/pubmed/28763058 http://dx.doi.org/10.1038/tp.2017.149 |