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A novel preventive therapy for paclitaxel-induced cognitive deficits: preclinical evidence from C57BL/6 mice

Chemotherapy-induced central nervous system (CNS) neurotoxicity presents an unmet medical need. Patients often report a cognitive decline in temporal correlation to chemotherapy, particularly for hippocampus-dependent verbal and visuo-spatial abilities. We treated adult C57Bl/6 mice with 12 × 20 mg ...

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Detalles Bibliográficos
Autores principales:	Huehnchen, P, Boehmerle, W, Springer, A, Freyer, D, Endres, M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2017
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611721/ https://www.ncbi.nlm.nih.gov/pubmed/28763058 http://dx.doi.org/10.1038/tp.2017.149

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