Pathogen-mediated NMDA receptor autoimmunity and cellular barrier dysfunction in schizophrenia

Autoantibodies that bind the N-methyl-D-aspartate receptor (NMDAR) may underlie glutamate receptor hypofunction and related cognitive impairment found in schizophrenia. Exposure to neurotropic pathogens can foster an autoimmune-prone environment and drive systemic inflammation leading to endothelial...

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Detalles Bibliográficos
Autores principales: Kannan, G, Gressitt, K L, Yang, S, Stallings, C R, Katsafanas, E, Schweinfurth, L A, Savage, C L G, Adamos, M B, Sweeney, K M, Origoni, A E, Khushalani, S, Bahn, S, Leweke, F M, Dickerson, F B, Yolken, R H, Pletnikov, M V, Severance, E G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611729/
https://www.ncbi.nlm.nih.gov/pubmed/28763062
http://dx.doi.org/10.1038/tp.2017.162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611729/
https://www.ncbi.nlm.nih.gov/pubmed/28763062
http://dx.doi.org/10.1038/tp.2017.162

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