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Rare genetic variants in CX3CR1 and their contribution to the increased risk of schizophrenia and autism spectrum disorders

CX3CR1, a G protein-coupled receptor solely expressed by microglia in the brain, has been repeatedly reported to be associated with neurodevelopmental disorders including schizophrenia (SCZ) and autism spectrum disorders (ASD) in transcriptomic and animal studies but not in genetic studies. To addre...

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Detalles Bibliográficos
Autores principales: Ishizuka, K, Fujita, Y, Kawabata, T, Kimura, H, Iwayama, Y, Inada, T, Okahisa, Y, Egawa, J, Usami, M, Kushima, I, Uno, Y, Okada, T, Ikeda, M, Aleksic, B, Mori, D, Someya, To, Yoshikawa, T, Iwata, N, Nakamura, H, Yamashita, T, Ozaki, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611740/
https://www.ncbi.nlm.nih.gov/pubmed/28763059
http://dx.doi.org/10.1038/tp.2017.173