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Decreased AGO2 and DCR1 in PBMCs from War Veterans with PTSD leads to diminished miRNA resulting in elevated inflammation

Chronic inflammation is a characteristic of post-traumatic stress disorder (PTSD). The initiation of inflammation and molecules involved are not yet clearly understood. Here, we provide compelling evidence that the inflammation seen in PTSD may result from the dysregulated miRNA processing pathway....

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Detalles Bibliográficos
Autores principales: Bam, M, Yang, X, Zumbrun, E E, Ginsberg, J P, Leyden, Q, Zhang, J, Nagarkatti, P S, Nagarkatti, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611749/
https://www.ncbi.nlm.nih.gov/pubmed/28850112
http://dx.doi.org/10.1038/tp.2017.185