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PET imaging of putative microglial activation in individuals at ultra-high risk for psychosis, recently diagnosed and chronically ill with schizophrenia

We examined putative microglial activation as a function of illness course in schizophrenia. Microglial activity was quantified using [(11)C](R)-(1-[2-chrorophynyl]-N-methyl-N-[1-methylpropyl]-3 isoquinoline carboxamide ((11)C-(R)-PK11195) positron emission tomography (PET) in: (i) 10 individuals at...

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Detalles Bibliográficos
Autores principales: Di Biase, M A, Zalesky, A, O'keefe, G, Laskaris, L, Baune, B T, Weickert, C S, Olver, J, McGorry, P D, Amminger, G P, Nelson, B, Scott, A M, Hickie, I, Banati, R, Turkheimer, F, Yaqub, M, Everall, I P, Pantelis, C, Cropley, V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611755/
https://www.ncbi.nlm.nih.gov/pubmed/28850113
http://dx.doi.org/10.1038/tp.2017.193