Development of a solid dosage platform for the oral delivery of bilayer vesicles

Within this work, we develop vesicles incorporating sub-unit antigens as solid dosage forms suitable for the oral delivery of vaccines. Using a combination of trehalose, dextran and mannitol, freeze-dried oral disintegrating tablets were formed which upon rehydration release bilayer vesicles incorpo...

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Detalles Bibliográficos
Autores principales: Wilkhu, Jitinder S., McNeil, Sarah E., Anderson, David E., Kirchmeier, Marc, Perrie, Yvonne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science B.V 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611758/
https://www.ncbi.nlm.nih.gov/pubmed/28619620
http://dx.doi.org/10.1016/j.ejps.2017.06.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611758/
https://www.ncbi.nlm.nih.gov/pubmed/28619620
http://dx.doi.org/10.1016/j.ejps.2017.06.014

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