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Phospho-Tau Accumulation and Structural Alterations of the Golgi Apparatus of Cortical Pyramidal Neurons in the P301S Tauopathy Mouse Model

The Golgi apparatus (GA) is a highly dynamic organelle involved in the processing and sorting of cellular proteins. In Alzheimer’s disease (AD), it has been shown to decrease in size and become fragmented in neocortical and hippocampal neuronal subpopulations. This fragmentation and decrease in size...

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Detalles Bibliográficos
Autores principales: Antón-Fernández, Alejandro, Merchán-Rubira, Jesús, Avila, Jesús, Hernández, Félix, DeFelipe, Javier, Muñoz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611801/
https://www.ncbi.nlm.nih.gov/pubmed/28922155
http://dx.doi.org/10.3233/JAD-170332