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Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death

Acute energy failure is one of the critical factors contributing to the pathogenic mechanisms of retinal ischemia. Our previous study demonstrated that glucose deprivation can lead to a caspase-dependent cell death of photoreceptors. The aim of this study was to decipher the upstream signal pathway...

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Detalles Bibliográficos
Autores principales: Fan, Bin, Wang, Bei-Fen, Che, Lin, Sun, Ying-Jian, Liu, Shu-Yan, Li, Guang-Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611869/
https://www.ncbi.nlm.nih.gov/pubmed/29085555
http://dx.doi.org/10.1155/2017/5093473