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Modeling GATAD1-Associated Dilated Cardiomyopathy in Adult Zebrafish

Animal models have played a critical role in validating human dilated cardiomyopathy (DCM) genes, particularly those that implicate novel mechanisms for heart failure. However, the disease phenotype may be delayed due to age-dependent penetrance. For this reason, we generated an adult zebrafish mode...

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Detalles Bibliográficos
Autores principales: Yang, Jingchun, Shah, Sahrish, Olson, Timothy M., Xu, Xiaolei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611887/
https://www.ncbi.nlm.nih.gov/pubmed/28955713
http://dx.doi.org/10.3390/jcdd3010006