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Pdgfrα functions in endothelial-derived cells to regulate neural crest cells and the development of the great arteries
Originating as a single vessel emerging from the embryonic heart, the truncus arteriosus must septate and remodel into the aorta and pulmonary artery to support postnatal life. Defective remodeling or septation leads to abnormalities collectively known as conotruncal defects, which are associated wi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Company of Biologists Ltd
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611965/ https://www.ncbi.nlm.nih.gov/pubmed/28714851 http://dx.doi.org/10.1242/dmm.029710 |