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PET Tau and Amyloid-β Burden in Mild Alzheimer’s Disease: Divergent Relationship with Age, Cognition, and Cerebrospinal Fluid Biomarkers

BACKGROUND: Combining PET amyloid-β (Aβ) and tau imaging may be critical for tracking disease progression in Alzheimer’s disease (AD). OBJECTIVE: We sought to characterize the relationship between Aβ and tau ligands as well as with other measures of pathology. METHODS: We conducted a multi-center ob...

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Detalles Bibliográficos
Autores principales: Koychev, Ivan, Gunn, Roger N., Firouzian, Azadeh, Lawson, Jennifer, Zamboni, Giovanna, Ridha, Basil, Sahakian, Barbara J., Rowe, James B., Thomas, Alan, Rochester, Lynn, Ffytche, Dominic, Howard, Robert, Zetterberg, Henrik, MacKay, Clare, Lovestone, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: IOS Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612013/
https://www.ncbi.nlm.nih.gov/pubmed/28800330
http://dx.doi.org/10.3233/JAD-170129