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Toxicological effects of NCKU-21, a phenanthrene derivative, on cell growth and migration of A549 and CL1-5 human lung adenocarcinoma cells

BACKGROUND: Chemotherapy insensitivity continues to pose significant challenges for treating non-small cell lung cancer (NSCLC). The purposes of this study were to investigate whether 3,6-dimethoxy-1,4,5,8-phenanthrenetetraone (NCKU-21) has potential activity to induce effective toxicological effect...

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Detalles Bibliográficos
Autores principales: Liao, Hsien-Feng, Pan, Chun-Hsu, Chou, Pei-Yu, Chen, Yi-Fong, Wu, Tian-Shung, Sheu, Ming-Jyh, Wu, Chieh-Hsi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612657/
https://www.ncbi.nlm.nih.gov/pubmed/28945763
http://dx.doi.org/10.1371/journal.pone.0185021